Azide/Carboxylic acid PEG reagent, Azido-PEG4-CH₂CO₂-t-Bu, Purity 98%

Synonym: 864681-04-9; Azido-PEG4-CH₂-Boc; 3,6,9,12-Tetraoxatetradecanoic acid, 14-azido-, 1,1-dimethylethyl ester; Azido-PEG4-CH₂CO₂-t-Bu; tert-butyl 14-AZIDO-3,6,9,12-TETRAOXATETRADECANOATE

CAS Number: 864681-04-9
PubChem CID: 59465087

Size

250 mg; 500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG4-CH₂CO₂-t-Bu ester features both an azide group and a t-butyl protected carboxylic acid within its structure. The presence of the azide allows it to engage in click chemistry reactions, while the protected carboxyl prevents self-coupling or polymerization during standard acid/amine or acid/hydroxyl coupling processes. The t-butyl ester can be deprotected through either acidic or basic hydrolysis methods, and the hydrophilic PEG spacer improves solubility in aqueous media.

Molecular Weight

333.4

Molecular Formula

C₁₄H₂₇N₃O₆

Functional Group 1

Azide

Functional Group 2

Acid

Functional Group 3

t-Butyl

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

This compound is commonly used in bioconjugation and organic synthesis. The azide group enables click chemistry reactions for conjugation, and the carboxylate and t-butyl groups offer possibilities for protection and controlled reactivity. It can be used to modify biomolecules or in the synthesis of small molecule conjugates for therapeutic or diagnostic purposes.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

Azide/Carboxylic acid PEG reagent, Azido-PEG4-CH2CO2-t-Bu, Purity 98%

Azide/Carboxylic acid PEG reagent, Azido-PEG4-CH₂CO₂-t-Bu, Purity 98%