Azide/Carboxylic acid PEG reagent, Azido-PEG5-acid, Purity 98%

Synonym: 1425973-16-5; Azido-PEG5-propionic acid; N₃-PEG5-CH₂CH₂COOH; 1-AZIDO-3,6,9,12,15-PENTAOXAOCTADECAN-18-OIC ACID

CAS Number: 1425973-16-5
PubChem CID: 77078450

Size

250 mg; 500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG5-acid serves as a water-soluble PEG linker. Its azide (N3) group can engage in reactions with alkynes like BCN or DBCO via click chemistry. Additionally, the terminal carboxylic acid can interact with primary amine groups when activated by agents such as EDC or HATU to create stable amide bonds.

Molecular Weight

335.4

Molecular Formula

C₁₃H₂₅N₃O₇

Functional Group 1

Acid

Functional Group 2

Azide

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Alkyne

Form

Solid

Purity

98%

Solubility

Water

Identity

Confirmed by NMR.

Applications

It can be used in the development of biosensors, where specific biomolecules can be immobilized on a surface for detection purposes. In drug discovery, it can be employed to modify drug candidates to improve their pharmacokinetic properties or to create prodrugs. It can also be used in the modification of biomaterials to enhance their interaction with cells or tissues.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.