Azide/Carboxylic acid PEG reagent, Azido-PEG6-acid, Purity 98%

Synonym: 361189-66-4; Azido-PEG6-Acid; N₃-PEG6-CH₂CH₂COOH; 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid; 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

CAS Number: 361189-66-4
PubChem CID: 59103378

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG6-acid serves as a water-soluble PEG linker that features both an azide and a terminal carboxylic acid group. The reactive azide (N3) can participate in click chemistry reactions with alkynes, BCN, or DBCO leading to stable triazole linkages being formed. Additionally, the terminal carboxylic acid may interact with primary amines when activated by agents such as EDC or HATU to create stable amide bonds.

Molecular Weight

379.4

Molecular Formula

C₁₅H₂₉N₃O₈

Functional Group 1

Acid

Functional Group 2

Azide

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Alkyne

Form

Solid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

This compound can be applied in bioconjugation reactions where the acid functionality can react with amine or alcohol groups. It is useful for modifying biomolecules or surfaces, and the PEG moiety enhances solubility and biocompatibility.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.