Description
Azido-PEG6-CH2CO2-t-Bu features an azide group along with a t-butyl ester. The PEG spacer enhances the solubility of this reagent in aqueous solutions. The azide can react with alkynes, BCN, or DBCO through click chemistry. Additionally, the t-butyl protected carboxylic acid can be deprotected under acidic conditions.
Applications
Azido-PEG6-CH2CO2-t-Bu is often employed in organic synthesis for the modification of molecules. The azide group enables click chemistry, and the carboxylate and t-butyl groups offer protection and controlled reactivity. It can be used in the synthesis of peptide conjugates or the modification of biomaterials.