Description
N-(acid-PEG10)-N-bis(PEG10-azide) is a widely used PEG reagent that includes one terminal carboxylic acid and two azide groups. The hydrophilic nature of the PEG spacer enhances solubility in aqueous solutions. Similar to previous products mentioned, these azides can react with alkynes, BCN, and DBCO through click chemistry processes leading to stable triazole linkages. Furthermore, the terminal carboxylic acid can also react with primary amines when activated by agents like EDC or HATU to form durable amide bonds.
Applications
In the field of polymer science, it can serve as a building block for the synthesis of complex polymer architectures with tailored properties. Additionally, it can be used in the modification of nanoparticles to improve their stability and targeting capabilities in biomedical applications.