Description
N-(Azido-PEG10)-N-(PEG10-NH-Boc)-PEG10-acid serves as a branched PEG linker that includes terminal azide, Boc-protected amine, and carboxylic acid groups. The hydrophilic nature of the PEG spacer enhances solubility in aqueous environments. The azide group can react with alkyne compounds like BCN or DBCO via click chemistry to form stable triazole linkages. Furthermore, the Boc group may be removed under mild acidic conditions to yield free amines.
Applications
This compound has multiple applications in biomaterials and drug delivery research. It can be used in the synthesis of complex polymer architectures for drug delivery, the modification of biomolecules for enhanced stability and targeting, or in the development of biomaterials with controlled surface properties and interactions.