Properties
Description
pGlu(15K)-PEG(2K)-pGlu(15K) is an amphiphile block polymer comprised of PEG and synthetic polyamino acid. The pGlu has one COOH function per glutamic acid unit and a terminal azide group. The azide moiety reacts with terminal alkyne in the presence of Cu catalyst or with cyclooctyne, such as DBCO or BCN to form a stable triazole bond.
Molecular Weight
pGlu(15 kDa), PEG(2 kDa), pGlu(15 kDa)
Functional Group 2
Carboxylic acid
Identity
Confirmed by NMR.
Applications
pGlu(15K)-PEG(2K)-pGlu(15K) can be used to enhance molecule delivery by improving the solubility and stability of active molecule agents.