Azide/Cysteine PEG reagent, APN-C3-PEG4-azide, Purity 98%

Synonym: 2183440-32-4; 1-Azido-N-(3-{[4-(2-cyanoeth-1-yn-1-yl)phenyl]carbamoyl}propyl)-3,6,9,12-tetraoxapentadecan-15-amide

CAS Number: 2183440-32-4
PubChem CID: 131954367

Size

5 mg; 10 mg; 25 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

APN-C3-PEG4-azide is a heterobifunctional linker featuring an APN moiety with exceptional chemoselectivity for cysteine and an azide group. Its stability in aqueous environments, human plasma, and living cells makes it a promising tool for thiol-click reactions in bioconjugation.

Molecular Weight

500.6

Molecular Formula

C₂₄H₃₂N₆O₆

Functional Group 1

Azide

Functional Group 2

Cysteine

Functional Group 3

None

Reactive Group 1

Thiol

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

APN-C3-PEG4-azide plays a crucial role in bioconjugation applications, facilitating specific and stable coupling of cysteine residues with azide-functionalized molecules. This enables precise labeling, imaging, and modification of biomolecules, including proteins and peptides, in various research areas such as proteomics, cell biology, and drug discovery.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.