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Azide/DMTr PEG reagent, DMTr-PEG12-azide, Purity 98%
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Cat. No.: X24-09-YYX468

Azide/DMTr PEG reagent, DMTr-PEG12-azide, Purity 98%

Synonym: 1-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-(4-methoxyphenyl)-phenylmethyl]-4-methoxybenzene

Size
100 mg; 250 mg
Price
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Datasheet
Datasheet
MSDS
MSDS
Properties
Description
DMTr-PEG12-azide is a linker that features a dimethoxytrityl-protected alcohol along with an azide group. The DMTr protecting group can be removed using a mild acid. The azide functionality can react with alkyne compounds, BCN, and DBCO through click chemistry methods to form stable triazole linkages. Additionally, the hydrophilic PEG spacer enhances solubility in aqueous solutions.
Molecular Weight
874
Molecular Formula
C45H67N3O14
Functional Group 1
Azide
Functional Group 2
DMTr
Functional Group 3
None
Reactive Group 1
Alkynyl
Reactive Group 2
Hydroxyl
Form
Solid
Purity
98%
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
It can be used in the synthesis of modified oligonucleotides for therapeutic or diagnostic purposes, such as antisense oligonucleotides or siRNAs. It can also be employed in the development of nucleic acid-based biosensors or drug delivery systems.
Storage
Store at -20°C.
For Research Use Only. Not For Clinical Use.
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