Azide/DOTA PEG reagent, DOTA-PEG10-azide, Purity 95%

Synonym: DOTA-PEG-azide; PEG10-DOTA-azide; Azide/DOTA PEG reagent

Size

5 mg; 10 mg; 25 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

The compound DOTA-PEG10-azide is a complex molecule with interesting structural characteristics. It combines a DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) moiety with a PEG10 chain terminated by an azide group. The PEG10 chain significantly enhances the solubility and biocompatibility of compounds, while the DOTA component provides coordination sites for metal ions. The azide group offers a reactive site for click chemistry reactions, allowing for facile conjugation with other molecules.

Molecular Weight

913

Molecular Formula

C₃₈H₇₂N₈O₁₇

Functional Group 1

Azide

Functional Group 2

DOTA

Functional Group 3

None

Reactive Group 1

Alkynyl

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

This compound has significant applications in medical imaging and targeted therapy. The DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) moiety can chelate various metal ions, such as gadolinium for magnetic resonance imaging (MRI) or radioactive isotopes for positron emission tomography (PET) imaging.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.