Cat. No.: X24-09-YYX444
Azide/DOTA PEG reagent, DOTA-PEG10-azide, Purity 95%
Synonym: DOTA-PEG-azide; PEG10-DOTA-azide; Azide/DOTA PEG reagent
Size
5 mg; 10 mg; 25 mg; 100 mg
Properties
Description
The compound DOTA-PEG10-azide is a complex molecule with interesting structural characteristics. It combines a DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) moiety with a PEG10 chain terminated by an azide group. The PEG10 chain significantly enhances the solubility and biocompatibility of compounds, while the DOTA component provides coordination sites for metal ions. The azide group offers a reactive site for click chemistry reactions, allowing for facile conjugation with other molecules.
Molecular Formula
C38H72N8O17
Identity
Confirmed by NMR.
Applications
This compound has significant applications in medical imaging and targeted therapy. The DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) moiety can chelate various metal ions, such as gadolinium for magnetic resonance imaging (MRI) or radioactive isotopes for positron emission tomography (PET) imaging.
For Research Use Only. Not For
Clinical Use.