Cat. No.: X24-09-YYX339
Azide/DOTA PEG reagent, DOTA-PEG5-azide, Purity 95%
Synonym: DOTA-PEG5-C2-azide; Azide/DOTA PEG reagent; DOTA-PEG5-azide
Size
1 mg; 5 mg; 10 mg; 25 mg
Properties
Description
DOTA-PEG5-azide features both DOTA and azide functionalities. DOTA acts as a chelating agent for cations, while azides are frequently utilized in copper-catalyzed click chemistry reactions with alkynes, BCN, and DBCO to form triazole linkages. The PEG linker enhances the water solubility of compounds in aqueous solutions.
Molecular Formula
C28H52N8O12
Identity
Confirmed by NMR.
Applications
The DOTA chelator can complex with radioactive metals such as gallium-68 or lutetium-177 for use in positron emission tomography (PET) imaging or targeted radiotherapy. The PEG5 moiety improves the pharmacokinetics and biodistribution of the radiolabeled compound.
For Research Use Only. Not For
Clinical Use.