Cat. No.: X24-09-YYX300
Azide/Ethylcarbamoyl PEG reagent, 20-(Azide-PEG3-ethylcarbamoyl)nonadecanoic-t-butyl ester, Purity 95%
Synonym: Azide-PEG3-ethylcarbamoyl nonadecanoate; t-butyl ester of 20-(Azide-PEG3-ethylcarbamoyl)nonadecanoic acid; PEG3-ethylcarbamoyl nonadecanoic azide ester; Nonadecanoic acid azide-PEG3 derivative
Size
100 mg; 250 mg; 500 mg; 1 g
Properties
Description
20-(Azide-PEG3-ethylcarbamoyl)nonadecanoic-t-butyl ester acts as a PEG linker incorporating an azide group and an alkane tail terminating with a t-butyl ester. Its azide moiety can react via click chemistry with alkyne compounds like BCN or DBCO to form stable triazole linkages. Additionally, the t-butyl protected carboxylic acid can be deprotected under acidic conditions. This polymer has the ability to spontaneously form micelles in aqueous solutions and may also serve as a precursor for more complex lipids intended for drug delivery nanoparticles.
Molecular Formula
C32H62N4O6
Functional Group 2
t-Butyl ester
Functional Group 3
Ethylcarbamoyl
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
It is often used in the modification of lipid molecules for the development of lipid-based drug delivery systems or for creating lipid membranes with specific properties.
For Research Use Only. Not For
Clinical Use.