Azide/Fmoc-protected amine PEG reagent, Fmoc-N-amido-PEG4-t-Boc-Hydrazide, Purity 98%

Synonym: 1263044-77-4; Fmoc-NH-PEG4-HZ-BOC; Fmoc-N-amido-PEG4-t-Boc-Hydrazide; 2-Boc-Hydrazino 3-Fmoc-Amino(peg4)propionamide

CAS Number: 1263044-77-4
PubChem CID: 51340972

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Fmoc-N-amido-PEG4-t-Boc-Hydrazide functions as a PEG reagent that includes an Fmoc-protected amine along with a Boc-protected hydrazide. Under basic conditions, the Fmoc group can be removed to yield free amines suitable for further conjugation reactions. The presence of the hydrophilic PEG spacer improves solubility in aqueous environments. Furthermore, the Boc protecting group can be deprotected under mild acidic conditions to generate a reactive hydrazide capable of coupling with various carbonyl groups thereafter.

Molecular Weight

601.7

Molecular Formula

C₃₁H₄₃N₃O₉

Functional Group 1

Boc

Functional Group 2

Azide

Functional Group 3

Fmoc

Reactive Group 1

Alkyne

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

It can be incorporated into peptide sequences for the development of peptide therapeutics or as a tool for studying peptide-protein interactions.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.