Azide/Fmoc-protected amine PEG reagent, N-Fmoc-N'-(azido-PEG4)-L-lysine- PFP ester, Purity 98%

Synonym: 2749985-69-9; Fmoc-NH-azide-PEG4-L-Lysine-PFP ester

CAS Number: 2749985-69-9

Size

250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-Fmoc-N'-(azido-PEG4)-L-lysine-PFP ester serves as a crosslinker featuring an Fmoc-protected amine and PFP-protected amine along with an azide group and lysine residue. The presence of the azide enables click chemistry reactions. Additionally, the PFP ester acts as a superior leaving group compared to hydroxyl groups and can be utilized to label primary amines t-found in proteins, amine-modified oligonucleotides, and other molecules containing amino groups. The hydrophilic nature of the PEG spacer enhances solubility in aqueous environments.

Molecular Weight

807.8

Molecular Formula

C₃₈H₄₂F₅N₅O₉

Functional Group 1

Azide

Functional Group 2

Ether

Functional Group 3

Fmoc

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

This compound can be used in peptide synthesis and modification, allowing for the incorporation of PEG and azide functionalities for specific applications such as targeted drug delivery.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.