Description
Azido-PEG1-methylamine is a PEG linker featuring a terminal azide group and a methylamine group. The azide group is highly reactive in Click Chemistry, forming stable triazole linkages with alkyne, BCN, or DBCO groups. The methylamine group reacts efficiently with carboxylic acids, activated NHS esters, and carbonyl compounds. The PEG1 spacer enhances solubility in aqueous media.
Applications
Azido-PEG1-methylamine is widely used in research for bioconjugation, surface modification, and creating multifunctional linkers. The azide group facilitates efficient Click Chemistry reactions, while the methylamine group enables covalent coupling with biomolecules, making it ideal for developing hydrophilic compounds and exploring chemical reactivity in experimental settings.