Azide/NHS PEG reagent, Azido-PEG1-NHS ester, Purity 98%

Synonym: 1807530-06-8; 2,5-DIOXOPYRROLIDIN-1-YL 3-(2-AZIDOETHOXY)PROPANOATE; AZIDO-PEG1-NHSESTER; N₃-PEG1-CH₂CH₂COONHS

CAS Number: 1807530-06-8
PubChem CID: 59470490

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG1-NHS ester is a versatile PEG reagent designed for click chemistry applications. The azide (N3) can react with alkyne compounds, BCN, and DBCO through click chemistry methods to form stable triazole linkages. Furthermore, the NHS ester can be utilized to label primary amines t-present in proteins, amine-modified oligonucleotides, and other molecules containing amines.

Molecular Weight

256.2

Molecular Formula

C₉H₁₂N₄O₅

Functional Group 1

Azide

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Alkynyl

Reactive Group 2

Amine

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

In bioconjugation chemistry, it is commonly used to attach biomolecules such as proteins, antibodies, or peptides. It provides a reactive site for covalent coupling, enabling the conjugation of PEG chains to these biomolecules, which can improve their solubility, stability, and pharmacokinetic properties.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.