Cat. No.: X24-09-YYX442
Azide/NHS PEG reagent, Azido-PEG10-NHS ester, Purity 98%
Synonym: 2801772-86-9; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Size
100 mg; 250 mg; 500 mg; 1 g
Properties
Description
Azido-PEG10-NHS ester is a monodisperse PEG linker that includes both azide and NHS ester functionalities. The hydrophilic nature of the PEG spacer enhances solubility in aqueous solutions. The azide group can engage in reactions with alkynes, BCN, and DBCO via click chemistry processes to form stable triazole linkages. Additionally, the NHS ester allows for labeling primary amines t-found in proteins, amine-modified oligonucleotides, and other molecules containing amines.
Molecular Formula
C27H48N4O14
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
It is commonly used in the development of antibody-drug conjugates, where drugs are attached to antibodies for targeted therapy.
For Research Use Only. Not For
Clinical Use.