Azide/NHS PEG reagent, Azido-PEG10-NHS ester, Purity 98%

Synonym: 2801772-86-9; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

CAS Number: 2801772-86-9

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG10-NHS ester is a monodisperse PEG linker that includes both azide and NHS ester functionalities. The hydrophilic nature of the PEG spacer enhances solubility in aqueous solutions. The azide group can engage in reactions with alkynes, BCN, and DBCO via click chemistry processes to form stable triazole linkages. Additionally, the NHS ester allows for labeling primary amines t-found in proteins, amine-modified oligonucleotides, and other molecules containing amines.

Molecular Weight

652.7

Molecular Formula

C₂₇H₄₈N₄O₁₄

Functional Group 1

Azide

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Alkynyl

Reactive Group 2

Amine

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

It is commonly used in the development of antibody-drug conjugates, where drugs are attached to antibodies for targeted therapy.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.