Azide/NHS PEG reagent, Azido-PEG12-NHS ester, Purity 98%

Synonym: 1108750-59-9; Azido-PEG12-NHS ester; 2363756-50-5; N₃-PEG12-CH₂CH₂COONHS ester; MFCD13184947

MDL: MFCD13184947
CAS Number: 2363756-50-5
PubChem CID: 51340930

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG12-NHS ester serves as a water-soluble crosslinker featuring both an azide group and an NHS ester functionality. The azide can engage in reactions with alkyne compounds like BCN or DBCO through click chemistry to form stable triazole linkages. Furthermore, the NHS ester can be utilized to label primary amines t-present in proteins, amine-modified oligonucleotides, and various other amino-containing molecules.

Molecular Weight

740.8

Molecular Formula

C₃₁H₅₆N₄O₁₆

Functional Group 1

NHS

Functional Group 2

Azide

Functional Group 3

Ether

Reactive Group 1

Alkyne

Reactive Group 2

Amine

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Azido-PEG12-NHS ester is commonly utilized for the conjugation of biomolecules, especially proteins and peptides. The NHS ester reacts with amine groups, and the PEG chain enhances solubility and stability.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.