Azide/NHS PEG reagent, Azido-PEG3-succinimidyl carbonate, Purity 98%

Synonym: 2110448-98-9; Azido-PEG3-succinimidyl carbonate; Azido-PEG3-O-NHS ester

CAS Number: 2110448-98-9
PubChem CID: 129012724

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG3-succinimidyl carbonate serves as a PEG linker that incorporates both azide and succinimidyl carbonate groups. The azide moiety can participate in copper-catalyzed click chemistry reactions with alkynes. Additionally, the succinimidyl carbonate group functions as an effective leaving group that typically reacts with amine nucleophiles. The hydrophilic nature of the PEG linker improves the compound's solubility in water.

Molecular Weight

360.3

Molecular Formula

C₁₃H₂₀N₄O₈

Functional Group 1

Azide

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

The succinimidyl carbonate group reacts with amino groups on proteins to attach the PEG3-azide moiety. This modification can improve protein stability, solubility, and pharmacokinetic properties.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.