Azide/NHS PEG reagent, Azido-PEG5-CH2CO2-NHS, Purity 95%

Cat. No.: X24-09-YYX314

Azide/NHS PEG reagent, Azido-PEG5-CH2CO2-NHS, Purity 95%

Synonym: 2144777-77-3; Azido-PEG5-CH2CO2-NHS; 2,5-dioxopyrrolidin-1-yl 17-azido-3,6,9,12,15-pentaoxaheptadecanoate; N3-PEG5-CH2COONHS

  • CAS Number: 2144777-77-3
  • PubChem CID: 131709291
Size
100 mg; 500 mg; 1 g
Price
Datasheet
MSDS
Properties
Description
Azido-PEG5-CH2CO2-NHS serves as an active pegylation reagent consisting of five PEG units. Its hydrophilic PEG spacer enhances solubility in aqueous environments. The azide group facilitates reactions with alkynes such as BCN or DBCO through click chemistry, leading to stable triazole linkages being formed. Furthermore, the NHS ester functionality allows it to label primary amines t-found in proteins, amine-modified oligonucleotides, and other amino-containing molecules.
Molecular Weight
418.4
Molecular Formula
C16H26N4O9
Functional Group 1
Azide
Functional Group 2
NHS
Functional Group 3
None
Reactive Group 1
Alkynyl
Reactive Group 2
Amine
Form
Solid
Purity
95%
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
It is often used in the conjugation of biomolecules, where the NHS group reacts with amine groups and the azide-PEG moiety provides solubility and functionality.
Storage
Store at -20°C.
For Research Use Only. Not For Clinical Use.

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