Cat. No.: X24-09-YYX314
Azide/NHS PEG reagent, Azido-PEG5-CH2CO2-NHS, Purity 95%
Synonym: 2144777-77-3; Azido-PEG5-CH2CO2-NHS; 2,5-dioxopyrrolidin-1-yl 17-azido-3,6,9,12,15-pentaoxaheptadecanoate; N3-PEG5-CH2COONHS
- CAS Number: 2144777-77-3
- PubChem CID: 131709291
Properties
Description
Azido-PEG5-CH2CO2-NHS serves as an active pegylation reagent consisting of five PEG units. Its hydrophilic PEG spacer enhances solubility in aqueous environments. The azide group facilitates reactions with alkynes such as BCN or DBCO through click chemistry, leading to stable triazole linkages being formed. Furthermore, the NHS ester functionality allows it to label primary amines t-found in proteins, amine-modified oligonucleotides, and other amino-containing molecules.
Molecular Formula
C16H26N4O9
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
It is often used in the conjugation of biomolecules, where the NHS group reacts with amine groups and the azide-PEG moiety provides solubility and functionality.
For Research Use Only. Not For
Clinical Use.