Azide/NHS PEG reagent, Azido-PEG5-NHS ester, Purity 98%

Synonym: 1433996-86-1; Azido-PEG5-NHS ester; 2,5-DIOXOPYRROLIDIN-1-YL 1-AZIDO-3,6,9,12,15-PENTAOXAOCTADECAN-18-OATE; Azido-PEG5-NHS; N₃-PEG5-SPA

CAS Number: 1433996-86-1
PubChem CID: 77078433

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG5-NHS ester functions as a PEG reagent designed for click chemistry applications. Its azide (N3) group can engage in reactions with alkynes such as BCN or DBCO via click chemistry processes resulting in stable triazole formations. The NHS ester allows for labeling primary amines t-found in proteins, amine-modified oligonucleotides, and other molecules containing amines. Furthermore, the hydrophilic nature of the PEG spacer improves solubility in water-based media.

Molecular Weight

432.4

Molecular Formula

C₁₇H₂₈N₄O₉

Functional Group 1

Azide

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Alkynyl

Reactive Group 2

Amine

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

Azido-PEG5-NHS ester is commonly used for the modification of biomolecules, especially proteins. The NHS ester reacts with amine groups on proteins, and the PEG chain improves the solubility and stability of the modified biomolecules. It can also be applied in the fabrication of biosensors or drug delivery systems.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.