Azide/NHS PEG reagent, Azido-PEG5-succinimidyl carbonate, Purity 98%

Synonym: AZIDO-PEG5-SUCCINIMIDYLCARBONATE; 2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl (2,5-dioxopyrrolidin-1-yl) carbonate

CAS Number: 1402411-88-4
PubChem CID: 129012719

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG5-succinimidyl carbonate consists of a PEG linker that includes active azide and succinimidyl carbonate functionalities. The azide can undergo copper-catalyzed click chemistry reactions involving alkynes, DBCO, and BCN. Meanwhile, succinimidyl carbonate acts as an effective leaving group that commonly reacts with amine nucleophiles. With five units of PEG included, this compound's water solubility is enhanced.

Molecular Weight

448.4

Molecular Formula

C₁₇H₂₈N₄O₁₀

Functional Group 1

Azide

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

This compound is commonly used for the modification of biomolecules, especially proteins and antibodies. It can be used in the development of antibody-drug conjugates (ADCs) or in the preparation of protein conjugates for imaging or therapeutic applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.