Description
Azido-PEG7-NHS ester is a widely used PEG reagent that features an azide group along with a terminal NHS ester. The hydrophilic nature of the PEG spacer enhances its solubility in water-based environments. The azide can engage in reactions with alkynes, BCN, and DBCO through click chemistry to form stable triazole linkages. Additionally, the NHS ester is suitable for labeling primary amines t-found in proteins, amine-modified oligonucleotides, and other amino-containing compounds.
Applications
This compound is frequently used in bioconjugation reactions. The NHS ester can react with amine groups on biomolecules such as proteins or peptides, while the azide-PEG moiety provides solubility and flexibility. It is commonly applied in the development of bioconjugates for drug delivery or diagnostic purposes.