Description
Azido-PEG4-CH2CO2-NHS serves as a PEG reagent designed for click chemistrythat includes both an azide group and an NHS ester. The hydrophilic nature of the PEG spacer enhances solubility in aqueous solutions. Similar to previous products mentioned, this azide can engage in reactions with alkyne compounds like BCN or DBCO via click chemistry processes resulting in stable triazole formations. The NHS ester functionality enables labeling of primary amines t-found in proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Applications
This compound is commonly used in bioconjugation reactions. The NHS ester group can react with amine groups on biomolecules such as proteins or antibodies, while the azide group enables further modification or conjugation through click chemistry.