Azide/Val-Cit dipeptide/PAB PEG reagent, Azido-PEG4-Val-Cit-PAB-OH, Purity 98%

Synonym: 2055024-64-9; Azido-PEG4-Val-Cit-PAB-OH; Azido-PEG(4)-Val-Cit-PAB

MDL: MFCD29918229
CAS Number: 2055024-64-9
PubChem CID: 119058238

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG4-Val-Cit-PAB-OH is a unique peptide linker designed for cleavable conjugation applications. The Val-Cit sequence is specifically cleaved by the enzyme Cathepsin B, allowing for controlled release of the linked molecules. The azido group incorporated into the linker enables facile conjugation via- click chemistry with DBCO, BCN, or other alkyne-functionalized molecules.

Molecular Weight

652.8

Molecular Formula

C₂₉H₄₈N₈O₉

Functional Group 1

Azide

Functional Group 2

Val-Cit dipeptide

Functional Group 3

PAB

Reactive Group 1

PNP

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

Azido-PEG4-Val-Cit-PAB-OH in drug delivery systems, targeted therapy, and biomolecule labeling where controlled release of payloads is desired. By exploiting the enzymatic activity of Cathepsin B, the linked cargo can be selectively released within the target cells or tissues, enhancing therapeutic efficacy while minimizing off-target effects.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.