BCN PEG reagent, Endo-BCN-PEG3-NHS ester, Purity 97%

Synonym: 2101206-94-2; Endo-BCN-PEG3-NHS ester; 2,5-Dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oate

CAS Number: 2101206-94-2
PubChem CID: 129896972

Size

50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG3-NHS ester labels primary amines (NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group enables copper-free click chemistry with azide-tagged biomolecules. The hydrophilic PEG spacer enhances solubility in aqueous media.

Molecular Weight

494.5

Molecular Formula

C₂₄H₃₄N₂O₉

Functional Group 1

BCN

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Azide

Form

Oil

Purity

97%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG3-NHS ester is crucial in bioconjugation, facilitating specific labeling of primary amines. Its copper-free click chemistry capability ensures efficient conjugation reactions. The hydrophilic PEG spacer improves compatibility with aqueous environments, making it suitable for various applications such as protein labeling, drug delivery, and biomaterials development.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.