BCN PEG reagent, Endo-BCN-PEG8-acid, Purity 98%

Synonym: 2126805-02-3; Endo-BCN-PEG8-acid; Rel-1-((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid; AKOS040741704; HY-140065

CAS Number: 2126805-02-3
PubChem CID: 146026236

Size

25 mg; 50 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG8-acid is a crosslinker reagent featuring a BCN group and a terminal carboxylic acid, crucial for bioconjugation applications.

Molecular Weight

617.7

Molecular Formula

C₃₀H₅₁NO₁₂

Functional Group 1

BCN

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Azide

Reactive Group 2

Amine

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG8-acid plays a vital role in bioconjugation chemistry by facilitating specific coupling reactions with primary amine groups using its terminal carboxylic acid. The BCN group enables copper-free click chemistry with azide-tagged biomolecules, broadening its applicability. Additionally, the amino group enhances versatility by reacting with various functional groups, including carboxylic acids, activated NHS esters, and carbonyls (ketone, aldehyde), allowing for precise molecular modifications and diverse applications in drug delivery.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.