BCN/Carboxyl PEG reagent, Endo-BCN-PEG4-t-butyl ester, Purity 95%

Synonym: 1807501-83-2; Endo-BCN-PEG4-t-butyl ester; Endo-BCN-PEG4-Boc; Tert-butyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate; Endo-BCN-PEG4-CH₂CH₂COOtBu

CAS Number: 1807501-83-2
PubChem CID: 91757930

Size

50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG4-t-butyl ester is a click chemistry linker with a BCN group and a t-butyl protected carboxyl group. The BCN group reacts with azide-tagged molecules. The protected carboxyl group prevents self-coupling or polymerization under standard coupling conditions. The t-butyl ester can be converted to a free acid under acidic conditions.

Molecular Weight

497.6

Molecular Formula

C₂₆H₄₃NO₈

Functional Group 1

BCN

Functional Group 2

Carboxyl

Functional Group 3

None

Reactive Group 1

Azide

Form

Oil

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG4-t-butyl ester plays a critical role in bioconjugation chemistry, enabling specific coupling reactions with azide-tagged molecules. The protected carboxyl group ensures stability during conjugation, preventing unwanted side reactions. After deprotection, the free acid functionality enhances versatility, allowing for further conjugation or modification. It finds applications in protein labeling, drug delivery, and biomaterials development.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.