Cat. No.: X24-03-YW0025
BCN/Carboxyl PEG reagent, t-Boc-aminooxy-PEG3-thiol, Purity 90%
Synonym: 1895922-75-4; t-Boc-aminooxy-PEG3-thiol; Boc-aminooxy-PEG3-thiol; Tert-butyl N-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]carbamate; Tert-butyl N-(2-{2-[2-(2-sulfanylethoxy)ethoxy]ethoxy}ethoxy)carbamate
- CAS Number: 1895922-75-4
- PubChem CID: 119058279
Size
100 mg; 250 mg; 500 mg
Properties
Description
t-Boc-aminooxy-PEG3-thiol is a crosslinker featuring a t-Boc-aminooxy group and a thiol group. The thiol group reacts with maleimide, OPSS, vinylsulfone, and transition metal surfaces including gold. The protected aminoxy can be deprotected under mild acidic conditions. The hydrophilic PEG spacer enhances solubility in aqueous media.
Molecular Formula
C13H27NO6S
Functional Group 2
Carboxyl
Reactive Group 1
Maleimide
Identity
Confirmed by NMR.
Applications
t-Boc-aminooxy-PEG3-thiol is crucial in bioconjugation, facilitating specific coupling reactions with maleimide, OPSS, vinylsulfone, and gold surfaces. After deprotection, the aminoxy group allows for further derivatization or conjugation with various functional groups. Its hydrophilic PEG spacer ensures compatibility with aqueous environments, making it suitable for diverse applications such as protein immobilization, surface modification, and drug delivery systems.
For Research Use Only. Not For
Clinical Use.