BCN/Carboxyl PEG reagent, t-Boc-aminooxy-PEG3-thiol, Purity 90%

Synonym: 1895922-75-4; t-Boc-aminooxy-PEG3-thiol; Boc-aminooxy-PEG3-thiol; Tert-butyl N-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]carbamate; Tert-butyl N-(2-{2-[2-(2-sulfanylethoxy)ethoxy]ethoxy}ethoxy)carbamate

CAS Number: 1895922-75-4
PubChem CID: 119058279

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-aminooxy-PEG3-thiol is a crosslinker featuring a t-Boc-aminooxy group and a thiol group. The thiol group reacts with maleimide, OPSS, vinylsulfone, and transition metal surfaces including gold. The protected aminoxy can be deprotected under mild acidic conditions. The hydrophilic PEG spacer enhances solubility in aqueous media.

Molecular Weight

325.4

Molecular Formula

C₁₃H₂₇NO₆S

Functional Group 1

BCN

Functional Group 2

Carboxyl

Functional Group 3

None

Reactive Group 1

Maleimide

Reactive Group 2

OPSS

Form

Liquid

Purity

90%

Identity

Confirmed by NMR.

Applications

t-Boc-aminooxy-PEG3-thiol is crucial in bioconjugation, facilitating specific coupling reactions with maleimide, OPSS, vinylsulfone, and gold surfaces. After deprotection, the aminoxy group allows for further derivatization or conjugation with various functional groups. Its hydrophilic PEG spacer ensures compatibility with aqueous environments, making it suitable for diverse applications such as protein immobilization, surface modification, and drug delivery systems.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.