BCN/NHS PEG reagent, Endo-BCN-PEG12-NHS ester, Purity 98%

Synonym: 2183440-26-6; Endo-BCN-PEG12-NHS ester

CAS Number: 2183440-26-6
PubChem CID: 129012711

Size

25 mg; 50 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG12-NHS ester is a water-soluble PEG linker featuring an NHS ester group and a BCN group. It is designed for labeling primary amines (-NH₂) in proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group facilitates copper-free click chemistry with azide-attached molecules.

Molecular Weight

891.0

Molecular Formula

C₄₂H₇₀N₂O₁₈

Functional Group 1

BCN

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Azide

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG12-NHS ester is essential in bioconjugation, enabling specific labeling of primary amines in biomolecules. Its aqueous solubility ensures compatibility with biological environments. The BCN group enhances versatility, allowing for efficient coupling reactions with azide-tagged biomolecules, making it valuable in protein labeling, drug delivery, and biomaterials development.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.