BCN/NHS PEG reagent, Endo-BCN-PEG4-NHS ester, Purity 95%

Synonym: 2252422-32-3; Endo-BCN-PEG4-NHS ester; Endo BCN-PEG4-NHS ester; (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(9-bicyclo[6.1.0]non-4-ynylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoate

CAS Number: 2252422-32-3
PubChem CID: 102514852

Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG4-NHS ester features a PEG linker, NHS ester group, and BCN moiety, essential for bioconjugation.

Molecular Weight

538.6

Molecular Formula

C₂₆H₃₈N₂O₁₀

Functional Group 1

BCN

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Azide

Form

Liquid

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG4-NHS ester is pivotal in labeling primary amines (-NH₂) of biomolecules. Its NHS ester group reacts specifically with primary amines, facilitating precise labeling of proteins, oligonucleotides, and other amine-containing molecules. The BCN group enables copper-free click chemistry with azide-tagged biomolecules, while the amino group further expands its versatility by reacting with various functional groups, including carboxylic acids and carbonyls. This enables diverse applications in drug delivery, diagnostics, and biomaterials research.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.