BCN/NHS PEG reagent, Endo-BCN-PEG8-NHS ester, Purity 98%

Synonym: 1608140-48-2; Endo-BCN-PEG8-NHS ester; Endo-bcn-peg8-nhsester; (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[[(1R,8S)-9-bicyclo[6.1.0]non-4-ynyl]methoxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate; SCHEMBL24801713

CAS Number: 1608140-48-2
PubChem CID: 146013013

Size

25 mg; 50 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG8-NHS ester is a monodisperse PEG linker featuring an NHS ester group and a BCN group. It labels primary amines (-NH₂) in proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group enables reaction with azide-tagged biomolecules under copper-free conditions. The hydrophilic PEG spacer enhances solubility in aqueous media.

Molecular Weight

714.8

Molecular Formula

C₃₄H₅₄N₂O₁₄

Functional Group 1

BCN

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Azide

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG8-NHS ester is crucial in bioconjugation, allowing specific labeling of primary amines. Its NHS ester functionality ensures efficient conjugation under mild conditions. The BCN group broadens its utility, facilitating coupling reactions with azide-tagged biomolecules. The hydrophilic PEG spacer improves compatibility with aqueous environments, making it suitable for various applications such as protein labeling, drug delivery, and biomaterials development.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.