Biotin PEG reagent, N-(Methyltetrazine-PEG4)-N-biotin-PEG4-NHS, Purity 95%

Synonym: N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-NHS; BP-28750

PubChem CID: 165430061

Size

10 mg; 25 mg; 50 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Methyltetrazine-PEG4)-N-biotin-PEG4-NHS is a specialized biotinylation reagent featuring a branched structure with a terminal NHS ester group and a methyltetrazine moiety. The NHS ester enables selective and efficient conjugation to primary amines on biomolecules, such as lysine residues or N-terminal amino groups, under mild physiological conditions (pH 7-9), forming stable amide bonds.

Molecular Weight

1,020.2

Molecular Formula

C₄₆H₆₉N₉O₁₅S

Functional Group 1

Biotin

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Lysine

Form

Reported

Purity

95%

Identity

Confirmed by NMR.

Applications

N-(Methyltetrazine-PEG4)-N-biotin-PEG4-NHS is an invaluable tool in various bioconjugation applications and chemical biology studies. It can be utilized for site-specific labeling of biomolecules, such as proteins, peptides, or nucleic acids, with biotin tags via- NHS ester chemistry, enabling subsequent detection, purification, or immobilization using streptavidin or avidin-based affinity methods.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.