Biotin/Cysteine PEG reagent, APN-C3-biotin, Purity 98%

Synonym: 2170240-97-6; Rel-N-(4-((4-(cyanoethynyl)phenyl)amino)-4-oxobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

CAS Number: 2170240-97-6
PubChem CID: 131954357

Size

25 mg; 50 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

APN-C3-biotin is a heterobifunctional linker featuring an APN moiety with exceptional chemoselectivity for cysteine and biotin. Its stability in aqueous environments, human plasma, and living cells makes it a promising thiol-click reaction tool.

Molecular Weight

453.6

Molecular Formula

C₂₃H₂₇N₅O₃S

Functional Group 1

Biotin

Functional Group 2

Cysteine

Functional Group 3

None

Reactive Group 1

Thiol

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

APN-C3-biotin is pivotal in bioconjugation applications, facilitating specific and stable coupling of cysteine residues with biotin. This enables precise labeling and detection of biomolecules, including proteins and peptides, in various research settings such as proteomics, cell biology, and drug discovery.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.