Biotin/DBCO PEG reagent, Dde biotin-PEG4-DBCO, Purity 95%

Synonym: 1807512-43-1; Dde biotin-PEG4-DBCO; Dde DBCO-Biotin; Ddebiotin-PEG4-DBCO

CAS Number: 1807512-43-1
PubChem CID: 136663253

Size

5 mg; 10 mg; 25 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Dde biotin-PEG4-DBCO is a specialized biotinylation reagent featuring a cleavable Dde protecting group, a PEG4 spacer, and a DBCO (dibenzocyclooctyne) functional group. This reagent specifically reacts with azide moieties via- copper-free Click Chemistry.

Molecular Weight

872.1

Molecular Formula

C₄₇H₆₁N₅O₉S

Functional Group 1

Biotin

Functional Group 2

DBCO

Functional Group 3

None

Reactive Group 1

Azide

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

Dde biotin-PEG4-DBCO finds application in various bioconjugation and labeling experiments where the selective attachment of biotin to azide-containing molecules is required. The Dde protecting group facilitates the efficient release of biotinylated molecules from streptavidin under mild conditions using hydrazine, enabling downstream applications such as protein purification, detection assays, and imaging studies.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.