Cat. No.: X24-03-YW0131
Biotin/Maleimide PEG reagent, Mal-cyclohexyl-PEG3-biotin, Purity 98%
Synonym: 2639395-45-0; Mal-Cyclohexyl-PEG3-Biotin; BP-25472
- CAS Number: 2639395-45-0
- PubChem CID: 155887621
Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Mal-cyclohexyl-PEG3-biotin is a PEG linker featuring a maleimide moiety and a biotin group. Maleimides selectively react with sulfhydryl groups to form stable thioether linkages under mildly acidic conditions (pH 6.5 - 7.5).
Molecular Formula
C30H47N5O8S
Functional Group 1
Biotin
Functional Group 2
Maleimide
Reactive Group 2
Sulfhydry
Identity
Confirmed by NMR.
Applications
Mal-cyclohexyl-PEG3-biotin is utilized for site-specific biotinylation of sulfhydryl-containing biomolecules, such as cysteine residues in proteins. This conjugation enables the attachment of biotin to target molecules for various applications including affinity purification, protein labeling, and detection assays. Additionally, the PEG spacer arm enhances solubility and flexibility, facilitating efficient binding interactions with streptavidin or avidin molecules.
For Research Use Only. Not For
Clinical Use.