Biotin/Maleimide PEG reagent, Mal-cyclohexyl-PEG3-biotin, Purity 98%

Synonym: 2639395-45-0; Mal-Cyclohexyl-PEG3-Biotin; BP-25472

CAS Number: 2639395-45-0
PubChem CID: 155887621

Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-cyclohexyl-PEG3-biotin is a PEG linker featuring a maleimide moiety and a biotin group. Maleimides selectively react with sulfhydryl groups to form stable thioether linkages under mildly acidic conditions (pH 6.5 - 7.5).

Molecular Weight

637.8

Molecular Formula

C₃₀H₄₇N₅O₈S

Functional Group 1

Biotin

Functional Group 2

Maleimide

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Sulfhydry

Form

Reported

Purity

98%

Identity

Confirmed by NMR.

Applications

Mal-cyclohexyl-PEG3-biotin is utilized for site-specific biotinylation of sulfhydryl-containing biomolecules, such as cysteine residues in proteins. This conjugation enables the attachment of biotin to target molecules for various applications including affinity purification, protein labeling, and detection assays. Additionally, the PEG spacer arm enhances solubility and flexibility, facilitating efficient binding interactions with streptavidin or avidin molecules.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.