Biotin/NHS/S-S disulfide bond PEG reagent, Biotin-bisamido-SS-NHS, Purity 98%

Synonym: 142439-92-7; Biotin-bisamido-SS-NHS; Biotin-bis-amido-SS-NHS; Biotin disulfide N-hydroxysuccinimide ester; NHS-SS-(+)-Biotin

CAS Number: 142439-92-7
PubChem CID: 71312116

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Biotin-bisamido-SS-NHS is a reagent grade cleavable linker designed to efficiently introduce a biotin moiety to amine-containing biomolecules with a cross-bridge and extended spacer arm.

Molecular Weight

575.7

Molecular Formula

C₂₂H₃₃N₅O₇S₃

Functional Group 1

Biotin

Functional Group 2

NHS

Functional Group 3

S-S disulfide bond

Reactive Group 1

BME

Reactive Group 2

DTT

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

Biotin-bisamido-SS-NHS is used in bioconjugation and molecular biology research, minimizing steric hindrance in binding to avidin or streptavidin probes, facilitating intracellular labeling, and enabling controlled release of the biotin label through disulfide bond cleavage using reducing agents like DTT, BME, and TCEP.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.