Properties
Description
N-Boc-PEG16-alcohol is a PEG linker featuring a terminal hydroxyl group and a Boc-protected amino group. The PEG16 spacer enhances solubility in aqueous media, providing hydrophilicity and biocompatibility. The hydroxyl group allows for versatile chemical modifications, while the Boc group offers acid-labile protection for controlled amine activation.
Molecular Formula
C37H75NO18
Functional Group 1
Boc-protected amine
Functional Group 2
Hydroxyl
Reactive Group 2
Nucleophile
Form
Liquid/Solid (low melting point)
Identity
Confirmed by NMR.
Applications
N-Boc-PEG16-alcohol is widely used in bioconjugation, drug delivery, and polymer synthesis. Its hydroxyl group supports further functionalization, and the Boc group enables precise deprotection to generate free amines, making it ideal for creating hydrophilic linkers and functionalized biomaterials in pharmaceutical research.