Description
t-Boc-Aminooxy-PEG11-alcohol is a PEG linker featuring a Boc-protected aminooxy group and a terminal hydroxyl group. The Boc group provides acid-labile protection, allowing controlled deprotection to expose the aminooxy group for specific reactions. The PEG11 spacer enhances solubility in aqueous environments, and the hydroxyl group offers flexibility for further derivatization.
Applications
t-Boc-Aminooxy-PEG11-alcohol is employed in research for synthesizing advanced biomolecular conjugates and studying aldehyde and ketone coupling reactions. The aminooxy group reacts selectively to form stable oxime linkages, while the hydroxyl group supports additional functionalization, making it suitable for developing hydrophilic linkers and exploring chemical reactivity in material and biochemical research.