Boc-protected amine/Iodine PEG reagent, t-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate, Purity 95%

Synonym: 1820026-89-8; Tert-butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate; BocNH-PEG2-CH₂CH₂I; Tert-butyl N-[2-[2-(2-iodoethoxy)ethoxy]ethyl]carbamate; Tert-butyl N-{2-[2-(2-iodoethoxy)ethoxy]ethyl}carbamate

CAS Number: 1820026-89-8
PubChem CID: 117965029

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate is a PEG-based linker featuring a Boc-protected amine and an iodine group. The Boc group provides acid-labile protection for the amine, while the iodine atom serves as an excellent leaving group for nucleophilic substitution. The hydrophilic PEG spacer enhances solubility in aqueous media.

Molecular Weight

359.2

Molecular Formula

C₁₁H₂₂INO₄

Functional Group 1

Boc-protected amine

Functional Group 2

Iodine

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Liquid

Purity

95%

Identity

Confirmed by NMR.

Applications

t-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate is used in organic synthesis, bioconjugation, and drug development. It facilitates nucleophilic substitution reactions and offers controlled amine deprotection under mild acidic conditions, making it ideal for targeted functionalization and the creation of complex molecular architectures in pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.