Boc-protected amine/Iodoacetamide PEG reagent, Iodoacetamido-PEG3-NHS ester, Purity 95%

Synonym: Iodoacetamido-PEG3-NHS ester

PubChem CID: 156026715

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Iodoacetamido-PEG3-NHS ester is a reactive PEG linker featuring an iodoacetamide group and an NHS ester, providing dual reactivity. The iodoacetamide acts as an efficient alkylating agent, forming covalent bonds with thiol groups, while the NHS ester enables rapid conjugation with primary amines under mild conditions.

Molecular Weight

486.3

Molecular Formula

C₁₅H₂₃IN₂O₈

Functional Group 1

Boc-protected amine

Functional Group 2

Iodoacetamide

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Solid

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Iodoacetamido-PEG3-NHS ester is used in site-specific protein labeling, bioconjugation, and drug delivery. It facilitates selective thiol modification of cysteine residues and efficient amine coupling, making it ideal for creating stable, targeted conjugates in biochemical and pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.