Boc-protected amine/Maleimide PEG reagent, 3,4-Dibromo-Mal-PEG2-Boc-amine, Purity 98%

Synonym: 1807537-43-4; 3,4-Dibromo-Mal-PEG2-N-Boc; Tert-butyl N-[2-[2-[2-(3,4-dibromo-2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethyl]carbamate; Tert-butyl N-(2-{2-[2-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}ethyl)carbamate

CAS Number: 1807537-43-4
PubChem CID: 77078278

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

3,4-Dibromo-Mal-PEG2-Boc-amine is a PEG derivative featuring a dibromomaleimide group and a Boc-protected amine. The dibromomaleimide allows two points of attachment via nucleophilic substitution of both bromine atoms. The Boc group, which is acid-labile, protects the amine group, enabling its deprotection under acidic conditions for further functionalization. The hydrophilic PEG spacer enhances the solubility of the compound in aqueous environments.

Molecular Weight

486.2

Molecular Formula

C₁₅H₂₂Br₂N₂O₆

Functional Group 1

Boc-protected amine

Functional Group 2

Maleimide

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

3,4-Dibromo-Mal-PEG2-Boc-amine is used in bioconjugation for creating stable linkages between thiol-containing molecules and amines. It is ideal for protein labeling, targeted drug delivery systems, and the preparation of multifunctional biomolecular conjugates in research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.