Cat. No.: X24-03-YW0696
Boc-protected aminooxy/Hydroxyl PEG reagent, t-Boc-Aminooxy-PEG8-alcohol, Purity 95%
Synonym: 2353410-14-5; Tert-Butyl ((23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosyl)oxy)carbamate; Tert-butyl N-[(23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)oxy]carbamate
- CAS Number: 2353410-14-5
- PubChem CID: 134811401
Size
100 mg; 250 mg; 500 mg
Properties
Description
t-Boc-Aminooxy-PEG8-alcohol is a water-soluble PEG reagent featuring a Boc-protected aminooxy group and a terminal hydroxyl group. The Boc-protected aminooxy group can be deprotected under mild acidic conditions to form a reactive aminooxy group, which reacts with aldehydes to create stable oxime linkages. The hydroxyl group provides flexibility for further derivatization.
Molecular Formula
C21H43NO11
Functional Group 1
Boc-protected aminooxy
Functional Group 2
Hydroxyl
Reactive Group 2
Aldehyde
Reactive Group 3
Nucleophile
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
t-Boc-Aminooxy-PEG8-alcohol is used in bioconjugation, drug delivery, and surface modification. Its aminooxy group facilitates selective coupling with aldehydes for creating oxime linkages, while the hydroxyl group supports additional functionalization, making it ideal for developing hydrophilic linkers and functional biomaterials in pharmaceutical and biomedical research.
For Research Use Only. Not For
Clinical Use.