Bromoacetamido PEG reagent, Bromo-PEG3-CH₂CO₂-t-Bu, Purity 98%

Synonym: 2100306-71-4; Bromo-PEG3-CH₂CO₂tBu; Bromo-PEG3-CH₂-Boc; Bromo-PEG3-CH₂COOtBu; Tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

CAS Number: 2100306-71-4
PubChem CID: 126480423

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromo-PEG3-CH₂CO₂tBu is a PEG linker featuring a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer enhances solubility in aqueous solutions, while the bromide serves as an effective leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group is susceptible to deprotection under acidic conditions.

Molecular Weight

327.2

Molecular Formula

C₁₂H₂₃BrO₅

Functional Group 1

Bromoacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Bromo-PEG3-CH₂CO₂tBu finds utility in bioconjugation and chemical modification reactions. Its bromide functionality facilitates nucleophilic substitution reactions, enabling the introduction of various functional groups or biomolecules. Moreover, the deprotection of the t-butyl carboxyl group allows for further derivatization, making it suitable for synthesizing diverse bioconjugates and molecular probes.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.

Bromoacetamido PEG reagent, Bromo-PEG3-CH2CO2-t-Bu, Purity 98%

Bromoacetamido PEG reagent, Bromo-PEG3-CH₂CO₂-t-Bu, Purity 98%