Bromoacetamido PEG reagent, Bromo-PEG4-CH₂CO₂-t-Bu, Purity 98%

Synonym: 1807505-29-8; Bromo-PEG4-CH₂CO₂tBu; Br-PEG4-CH₂-Boc; Bromo-peg4-ch2co2tbutyl ester; Bromo-PEG4-CH₂COOtBu

CAS Number: 1807505-29-8
PubChem CID: 77078232

Size

500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromo-PEG4-CH₂CO₂tBu is a PEG linker comprising a bromide group and a t-butyl protected carboxyl group. Its hydrophilic PEG spacer enhances solubility in aqueous media. The bromide (Br) serves as an effective leaving group for nucleophilic substitution reactions, while the t-butyl protected carboxyl group can be deprotected under acidic conditions.

Molecular Weight

371.3

Molecular Formula

C₁₄H₂₇BrO₆

Functional Group 1

Bromoacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Bromo-PEG4-CH₂CO₂tBu is employed in bioconjugation and chemical modification reactions due to its versatile reactivity. The bromide functionality facilitates nucleophilic substitution reactions, enabling the introduction of various functional groups or biomolecules. Additionally, the deprotection of the t-butyl carboxyl group offers further derivatization possibilities, making it suitable for synthesizing diverse bioconjugates and molecular probes.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.

Bromoacetamido PEG reagent, Bromo-PEG4-CH2CO2-t-Bu, Purity 98%

Bromoacetamido PEG reagent, Bromo-PEG4-CH₂CO₂-t-Bu, Purity 98%