Bromoacetamido PEG reagent, Bromoacetamido-PEG3-t-butyl ester, Purity 98%

Synonym: 1807537-33-2; Bromoacetamido-PEG3-t-butyl ester; Bromoacetamido-PEG3-C2-Boc; Tert-butyl 1-bromo-2-oxo-6,9,12-trioxa-3-azapentadecan-15-oate; BROMOACETAMIDO-PEG3-t-BUTYLESTER

CAS Number: 1807537-33-2
PubChem CID: 91757751

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromoacetamido-PEG3-t-butyl ester is a PEG linker comprising a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer enhances solubility in aqueous environments. With its bromide moiety, it serves as an effective leaving group for nucleophilic substitution reactions. Additionally, the t-butyl protected carboxyl group is susceptible to deprotection under acidic conditions.

Molecular Weight

398.3

Molecular Formula

C₁₅H₂₈BrNO₆

Functional Group 1

Bromoacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bromoacetamido-PEG3-t-butyl ester finds utility in bioconjugation and chemical modification endeavors. Its bromide functionality facilitates conjugation with various nucleophiles, enabling the synthesis of bioconjugates or modified molecules. The t-butyl protected carboxyl group offers versatility, allowing for controlled release or activation through deprotection under acidic conditions, thereby making it suitable for drug delivery or biomaterial applications.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.