Bromoacetamidoacetamido/NHS PEG reagent, Bromoacetamido-PEG4-NHS ester, Purity 98%

Synonym: 1260139-70-5; Bromoacetamido-PEG4-NHS ester; 2,5-Dioxopyrrolidin-1-yl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate; Bromoacetamido-PEG4-NHS; SCHEMBL1577786

CAS Number: 1260139-70-5
PubChem CID: 77078534

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromoacetamido-PEG4-NHS ester is a versatile PEG linker incorporating a bromide group and an NHS ester functionality. With its hydrophilic PEG spacer, this compound demonstrates enhanced solubility in aqueous environments. The bromide serves as an excellent leaving group, facilitating nucleophilic substitution reactions. Meanwhile, the NHS ester moiety enables selective labeling of primary amines (-NH2) on proteins, amine-modified oligonucleotides, and similar amine-containing molecules.

Molecular Weight

483.3

Molecular Formula

C₁₇H₂₇BrN₂O₉

Functional Group 1

Bromoacetamidoacetamido

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Form

Oil

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Bromoacetamido-PEG4-NHS ester can be used in bioconjugation and chemical biology studies. Its NHS ester group allows for efficient and site-specific labeling of biomolecules with primary amines, enabling the attachment of various probes, dyes, or other functional groups.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.