Carbonate/NHS PEG reagent, m-PEG3-succinimidyl carbonate, Purity 98%

Synonym: 477775-77-2; m-PEG3-succinimidyl carbonate; mPEG3-SC; N-Hydroxysuccinimide MeO-Peg3 carbonate; 2,5-Dioxopyrrolidin-1-yl (2-(2-(2-methoxyethoxy)ethoxy)ethyl) carbonate

CAS Number: 477775-77-2
PubChem CID: 51340961

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

m-PEG3-succinimidyl carbonate serves as a PEG linker characterized by its succinimidyl carbonate end group which exhibits reactivity towards amines, forming stable amide bonds upon reaction. The presence of this hydrophilic PEG linker enhances the compound's water solubility properties when placed into aqueous media.

Molecular Weight

305.3

Molecular Formula

C₁₂H₁₉NO₈

Functional Group 1

Carbonate

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Form

Solid or viscous liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

This compound is used as a reactive linker in bioconjugation processes. The succinimidyl carbonate group is highly reactive towards amine-containing nucleophiles, allowing for the attachment of PEG chains to proteins or other biomolecules for enhanced solubility and stability.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.