Description
This substance features a 6-unit PEG chain with an acid group at one end and a t-butyl ester group at the other. The t-butyl ester can be used for protection and the acid group enables various coupling reactions. The hydrophilic PEG spacer increases solubility in aqueous solutions, and the t-butyl protected carboxyl group can be deprotected under acidic conditions.
Applications
Acid-PEG6-t-butyl ester can be utilized in the protection and modification of carboxylic acids during synthesis reactions. In drug development, it can be part of the design of prodrugs or drug conjugates.