Description
Bis-PEG13-acid comprises two terminal carboxylic acid groups embedded within a PEG linker. Its hydrophilic PEG spacer enhances solubility in aqueous environments. The carboxylic acids facilitate the formation of stable amide bonds with primary amine groups, catalyzed by activators like EDC or HATU.
Applications
Bis-PEG13-acid is extensively employed in bioconjugation and crosslinking applications. It serves as a crucial linker for attaching biomolecules to surfaces, nanoparticles, or other carriers via- amide bond formation. Additionally, it finds utility in the synthesis of advanced materials and drug delivery systems, where precise control over linker properties is pivotal for optimizing performance and biocompatibility.